This sub-region (called "Nouveau-Rhône" since January 2015) is one of the oldest wine-making areas in France. The Rhône climate is continental, oceanic and semicontinental, with alternating influences from the Mediterranean. Winters are quite rigorous (sometimes with strong frost and occasional snowfalls), while summers are warm and sunny. The local vintners cultivate 21 grape varietis - 13 red and 8 white - and produces a great deal of high quality wines.

The red varieties are Grenache, Shiraz, Mourvèdre, Carignan, Cinsault, Muscardin, Brun Argenté (or Vaccarèse),
Piquepoul rouge, Terret Noir.

The white varieties are Grenache blanc, Clairette blanche, Marsanne, Roussanne, Borboëne, Vionniere, Trebbiano, Piquepoul blanc.